Table 3.
Items | All-cause mortality | Cardiovascular death | Composite endpoint events | ||||||
---|---|---|---|---|---|---|---|---|---|
P | HR | 95% CI | P | HR | 95% CI | P | HR | 95% CI | |
Male | 0.034 | 2.442 | 1.069–5.574 | 0.050 | 2.374 | 0.999–5.641 | 0.052 | 1.73 | 0.995–3.010 |
Age | 0.100 | 1.033 | 0.994–1.074 | 0.185 | 1.028 | 0.987–1.070 | 0.006 | 1.035 | 1.010–1.061 |
Hypertension | 0.846 | 0.916 | 0.376–2.228 | 0.991 | 1.005 | 0.390–2.594 | 0.126 | 1.673 | 0.865–3.236 |
Prior stroke | 0.269 | 1.748 | 0.649–4.710 | 0.481 | 1.478 | 0.498–4.397 | 0.002 | 2.591 | 1.412–4.754 |
Diabetes mellitus | 0.003 | 3.525 | 1.525–8.146 | 0.012 | 3.010 | 1.268–7.146 | 0.017 | 1.904 | 1.124–3.226 |
Smoking | 0.226 | 0.588 | 0.249–1.390 | 0.200 | 0.552 | 0.222–1.370 | 0.443 | 0.813 | 0.479–1.380 |
Left ventricular eject fraction | 0.049 | 0.964 | 0.930–1.000 | 0.041 | 0.962 | 0.927–0.998 | 0.255 | 0.984 | 0.958–1.012 |
LVEDD | 0.650 | 1.019 | 0.940–1.104 | 0.475 | 1.030 | 0.950–1.117 | 0.261 | 1.029 | 0.979–1.082 |
Hemoglobin | 0.013 | 0.972 | 0.950–0.994 | 0.034 | 0.975 | 0.952–0.998 | 0.000 | 0.973 | 0.958–0.988 |
Serum creatinine | 0.789 | 1.000 | 0.997–1.003 | 0.959 | 1.000 | 0.997–1.003 | 0.003 | 1.002 | 1.001–1.004 |
eGFR | 0.174 | 0.990 | 0.977–1.004 | 0.397 | 0.994 | 0.979–1.008 | 0.000 | 0.983 | 0.975–0.992 |
Triglyceride | 0.373 | 0.819 | 0.528–1.271 | 0.352 | 0.799 | 0.498–1.282 | 0.469 | 1.081 | 0.875–1.337 |
LDL-C | 0.839 | 1.048 | 0.666–1.649 | 0.649 | 0.891 | 0.543–1.463 | 0.141 | 0.790 | 0.578–1.081 |
ACEI/ARB | 0.010 | 0.295 | 0.116–0.749 | 0.009 | 0.261 | 0.096–0.713 | 0.001 | 0.386 | 0.222–0.673 |
Beta-receptor blocker | 0.484 | 1.395 | 0.550–3.538 | 0.668 | 1.230 | 0.477–3.171 | 0.316 | 1.345 | 0.753–2.403 |
RAS | 0.000 | 4.494 | 1.939–10.414 | 0.008 | 3.458 | 1.391–8.594 | 0.001 | 2.759 | 1.523–4.999 |
eGFR was calculated by CKD-EPI equation. ACEI/ARB: Angiotensin-converting enzyme inhibitor/angiotensin-receptor blocker; LVEDD: Left ventricular end diastolic diameter; RAS: Renal artery stenosis; eGFR: Estimated glomerular filtration rate; HR: Hazard ratio; CI: Confidence interval; LDL-C: Low-density lipoprotein cholesterol.