Table 2.
Genes upregulated in hBMSCs by DEX treatment. Human genes upregulated by at least threefold in hBMSCs treated with DEX for 6 h at P5 compared with nontreated cells.
| Genes | Gene bank | Log2 ratio | |
|---|---|---|---|
| FKBP5 | FK506 binding protein 5 | NM_004117 | 3.932 |
| CYP19A1 | Cytochrome P450, family 19, subfamily A, polypeptide 1, transcript variant 2 | NM_031226 | 3.880 |
| HEYL | Hairy/enhancer-of-split related to YRPW motif-like | NM_014571 | 3.162 |
| BMP6 | Bone morphogenetic protein 6 | NM_001718 | 3.006 |
| DKK1 | Dickkopf homolog 1 (Xenopus laevis) | NM_012242 | 2.889 |
| TNFAIP8L3 | Tumor necrosis factor, alpha-induced protein 8-like 3 | NM_207381 | 2.685 |
| INHBB | Inhibin, beta B | NM_002193 | 2.653 |
| MYPN | Myopalladin | NM_032578 | 2.594 |
| CPM | Carboxypeptidase M, transcript variant 1 | NM_001874 | 2.590 |
| XIRP1 | Xin actin-binding repeat containing 1 | NM_194293 | 2.543 |
| FOXO1 | Forkhead box O1 | NM_002015 | 2.413 |
| CDH15 | Cadherin 15, type 1, M-cadherin (myotubule) | NM_004933 | 2.377 |
| GAL | Galanin prepropeptide | NM_015973 | 2.345 |
| SNCAIP | Synuclein, alpha interacting protein | NM_005460 | 2.338 |
| RNF128 | Ring finger protein 128, transcript variant 1 | NM_194463 | 2.293 |
| PRICKLE2 | Prickle homolog 2 (Drosophila) | NM_198859 | 2.289 |
| ADRA1B | Adrenergic, alpha-1B-, receptor | NM_000679 | 2.267 |
| PTGER2 | Prostaglandin E receptor 2 (subtype EP2), 53 kDa | NM_000956 | 2.254 |
| PPP1R14C | Protein phosphatase 1, regulatory (inhibitor) subunit 14C | NM_030949 | 2.234 |
| WISP1 | WNT1 inducible signaling pathway protein 1, transcript variant 2 | NM_080838 | 2.220 |
| ANGPTL4 | Angiopoietin-like 4, transcript variant 1 | NM_139314 | 2.201 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | NM_004675 | 2.173 |
| ZNF469 | Zinc finger protein 469 | NM_001127464 | 2.145 |
| CRYGS | Crystallin, gamma S | NM_017541 | 2.140 |
| MT1M | Metallothionein 1M | NM_176870 | 2.121 |
| SHC4 | SHC (Src homology 2 domain containing) family, member 4 | NM_203349 | 2.070 |
| SGEF | Src homology 3 domain-containing guanine nucleotide exchange factor | NM_015595 | 2.046 |
| TET3 | Tet oncogene family member 3 | NM_144993 | 2.019 |
| PAG1 | Phosphoprotein associated with glycosphingolipid microdomains 1 | NM_018440 | 1.986 |
| EEPD1 | Endonuclease/exonuclease/phosphatase family domain containing 1 | NM_030636 | 1.980 |
| SLC20A1 | Solute carrier family 20 (phosphate transporter), member 1 | NM_005415 | 1.971 |
| CMKLR1 | Chemokine-like receptor 1, transcript variant 1 | NM_001142343 | 1.970 |
| FABP5 | Fatty acid binding protein 5 (psoriasis-associated) | NM_001444 | 1.948 |
| ABLIM3 | Actin binding LIM protein family, member 3 | NM_014945 | 1.944 |
| SEC14L2 | SEC14-like 2 (S. cerevisiae), transcript variant 1 | NM_012429 | 1.942 |
| CAMK2N1 | Calcium/calmodulin-dependent protein kinase II inhibitor 1 | NM_018584 | 1.906 |
| HS3ST3B1 | Heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1 | NM_006041 | 1.839 |
| KBTBD11 | Kelch repeat and BTB (POZ) domain containing 11 | NM_014867 | 1.829 |
| WNT5B | Wingless-type MMTV integration site family, member 5B, transcript variant 2 | NM_030775 | 1.817 |
| SLA | Src-like adaptor, transcript variant 1 | NM_001045556 | 1.788 |
| MT1G | Metallothionein 1G | NM_005950 | 1.781 |
| MT1A | Metallothionein 1A | NM_005946 | 1.780 |
| TOP1 | Topoisomerase (DNA) I | NM_003286 | 1.771 |
| MTSS1 | Metastasis suppressor 1 | NM_014751 | 1.765 |
| BAIAP2 | BAI1-associated protein 2, transcript variant 3 | NM_006340 | 1.750 |
| IRAK3 | Interleukin-1 receptor-associated kinase 3, transcript variant 1 | NM_007199 | 1.740 |
| MT1B | Metallothionein 1B | NM_005947 | 1.734 |
| FADS1 | Fatty acid desaturase 1 | NM_013402 | 1.725 |
| ABTB2 | Ankyrin repeat and BTB (POZ) domain containing 2 | NM_145804 | 1.715 |
| JARID2 | Jumonji, AT rich interactive domain 2 | NM_004973 | 1.686 |
| ITGA5 | Integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | NM_002205 | 1.652 |
| MT1X | Metallothionein 1X | NM_005952 | 1.647 |
| GJB3 | Gap junction protein, beta 3, 31 kDa, transcript variant 1 | NM_024009 | 1.645 |
| MT1H | Metallothionein 1H | NM_005951 | 1.639 |
| HIVEP3 | Human immunodeficiency virus type I enhancer binding protein 3 | NM_024503 | 1.619 |
| TCF7 | Transcription factor 7 (T-cell specific, HMG-box), transcript variant 1 | NM_003202 | 1.617 |
| NR2F1 | Nuclear receptor subfamily 2, group F, member 1 | NM_005654 | 1.613 |
A total of 28,780 human genes consistent with the quality criteria, genes upregulated threefold or higher are listed.