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Effect of BAPTA on ammonia-induced NADPH oxidase (NOX) activity. Cultures were exposed to ammonia (5 mM NH4Cl), and NOX activity was determined. Ammonia significantly increased NOX activity at 5 min and 2 h. Pretreatment (15 min) of cultures with BAPTA significantly diminished NOX activity. *p<0.05 vs. control; **p<0.01 vs. NH4.
