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. 2015 Nov 2;46(1):185–191. doi: 10.1002/eji.201545757

Figure 2.

Figure 2

KIR2DL3+ and KIR2DL1+ NKC are sensitive to disarming by KIR2DS1. Functional response (CD107a) of indicated single receptor positive NKC subsets (SP) to K562 stimulation was compared with subsets co‐expressing the single inhibitory receptor with KIR2DS1. Seven healthy volunteer donors carried KIR2DS1, and all were C1/C2, Bw4+. Each circle is from one donor with indicated receptor expression. Connected lines indicate populations from the same donor. Seven healthy control individuals carried KIR2DS1 and HLA‐C2, and were also C1+/Bw4+. Each circle shown is the mean %CD107a+ minus value from PBMCs alone from a single individual with indicated receptor expression. Wilcoxon signed rank test (two‐tailed), *p < 0.05.