Table 1.
Demographic and clinical data for the three groups
| HC (n = 17) | DLB (n = 18) | PDD (n = 12) | p‐value | |
|---|---|---|---|---|
| Gender M:F | 14:3 | 13:5 | 11:1 | χ 2 = 1.79, p = 0.407a |
| Age | 76.88 ± 5.8 | 77.17 ± 6.1 | 71.5 ± 4.8 | F(2,44) = 4.2, p = 0.022b |
| MMSE | 29.1 ± 0.9 | 23.6 ± 3.9 | 22.5 ± 5.2 | t 28 = 0.66, p = 0.51c |
| CAMCOG | 96.4 ± 3.3 | 76.2 ± 13 | 75.8 ± 14.6 | t 28 = 0.07, p = 0.94c |
| CAMCOG atten | 6.7 ± 0.56 | 4.5 ± 2.12 | 4.0 ± 2.0 | t 28 = 0.64, p = 0.52c |
| CAMCOG exec | 22.9 ± 2.7 | 13.5 ± 5.12 | 14.17 ± 1.94 | t 28 = 0.42,p = 0.67c |
| NPI hall | na | 1.65 ± 1.83d | 2.6 ± 2.3 | t 27 = 1.21, p = 0.23c |
| UPDRS | 1.41 ± 1.87 | 17.4 ± 7.8 | 26.4 ± 9.0 | t 28 = 2.9, p < 0.007c |
| CAF | na | 3.29 ± 4.0d | 6.1 ± 3.4e | t 25 = 1.83, p = 0.08c |
| PD‐CI years | na | 0.53 ± 1.8f | −7.5 ± 4.42 | p < 0.001g |
| Cog. symptoms years | na | 3.63 ± 2.58 | 2.79 ± 1.7 | p = 0.366g |
Values expressed as mean ± 1 SD.
Abbreviations: HC, healthy controls; DLB, dementia with Lewy bodies; PDD, Parkinson's disease dementia; MMSE, Mini‐Mental State Examination; CAMCOG, Cambridge Cognitive Examination; CAMCOG atten, attention subscore; CAMCOG exec, executive subscore; NPI, Neuropsychiatric Inventory; CAF, Clinical Assessment of Fluctuations; UPDRS, Unified Parkinson's Disease Rating Scale; PD‐CI years, age at onset of Parkinsonism minus age at onset of cognitive impairment; cog‐symptoms, duration of cognitive impairment in years; na, not applicable.
a
Chi‐square test.
b
Anova.
c
Student's t‐test – DLB vs PDD.
d
n = 17.
e
n = 10.
f
n = 15.
g
Mann–Whitney U‐test.