Table 1.
Numbers of controls and cases by sex, age, histological subtype, history of IM and study
| Controls N (%) | All cases N (%) | EBV+ve cases N (%) | EBV‐ve cases N (%) | ||
|---|---|---|---|---|---|
| Total participants | 347 | 503 | 155 | 348 | |
| Sex | Female | 144 (41) | 225 (45) | 49 (32) | 176 (51) |
| Male | 203 (59) | 278 (55) | 106 (68) | 172 (49) | |
| Age group (years) | 15‐34 | 131 (38) | 272 (54) | 61 (39) | 211 (61) |
| 35‐49 | 81 (23) | 99 (20) | 31 (20) | 68 (20) | |
| ≥50 | 135 (39) | 132 (26) | 63 (41) | 69 (20) | |
| Histological subtype | Mixed cellularity | 115 (23) | 63 (41) | 52 (15) | |
| Nodular sclerosis | 353 (70) | 79 (51) | 274 (79) | ||
| Other | 35 (7) | 13 (8) | 22 (6) | ||
| Self‐reported IM | Not recorded | 12 | 201 | 70 | 131 |
| No | 316 (94) | 268 (89) | 72 (85) | 196 (90) | |
| Yes | 19 (6) | 34 (11) | 13 (15) | 21 (10) | |
| Study | SNEHD | 320 (92) | 283 (56) | 82 (53) | 201 (58) |
| YHHCCS | 27 (8) | 41 (8) | 10 (6) | 31 (9) | |
| ITCH | 0 (0) | 179 (36) | 63 (41) | 116 (33) | |
All cases, all cHL cases; EBV+ve cases, EBV‐positive cHL cases; EBV‐ve cases, EBV‐negative cHL cases; N, number; IM, infectious mononucleosis; SNEHD, Scotland and Newcastle Epidemiological study of Hodgkin's Disease; YHHCCS, Young adult Hodgkin disease and Haematological malignancy Case Control Study; ITCH, Investigation of The Cause of Hodgkin lymphoma, a cHL case series.