Table 1.
Significant SNPs in Chr8p21.3 next to GFRA2
Chr | SNP | Position | Gene | Minor allele | Allele frequency in cases (%) | Allele frequency in controls (%) | p‐value | OR | Information about the SNP |
---|---|---|---|---|---|---|---|---|---|
8 | rs4872521 | 21707713 | Intergenic | G | 21.53 | 28.82 | 5.40 × 10−7 | 0.68 | Imputed |
8 | rs4872522 | 21707844 | Intergenic | C | 21.53 | 28.78 | 6.47 × 10−7 | 0.68 | Imputed |
8 | rs10098807 | 21708824 | Intergenic | A | 21.63 | 28.84 | 7.00 × 10−7 | 0.68 | Imputed |
8 | rs11774105 | 21710146 | Intergenic | C | 21.72 | 29.06 | 4.03 × 10−7 | 0.68 | Imputed |
8 | rs17428041 | 21711431 | Intergenic | C | 21.53 | 29.08 | 1.77 × 10−7 | 0.67 | In the Illumina OmniExpress |
8 | rs17615364 | 21711580 | Intergenic | A | 21.58 | 29.08 | 2.20 × 10−7 | 0.67 | Imputed |
8 | rs11776842 | 21711651 | Intergenic | C | 21.58 | 29.08 | 2.20 × 10−7 | 0.67 | Imputed |
8 | rs12545534 | 21712401 | Intergenic | A | 21.58 | 29.02 | 2.62 × 10−7 | 0.67 | In the Illumina OmniExpress |
8 | rs11780601 | 21717841 | Intergenic | T | 18.79 | 25.63 | 7.98 × 10−7 | 0.67 | In the Illumina OmniExpress |
p‐values and ORs were calculated using Fisher's exact test. Chr, chromosome; SNP, single nucleotide polymorphisms; OR, odds ratio.