Skip to main content
. 2015 Mar 18;63(12):2133–2151. doi: 10.1002/glia.22821

Figure 1.

Figure 1

Astrocytes express various receptor types in their perisynaptic processes. (A) Silver‐enhanced (small grains) glutamine synthetase‐positive glial processes in the stratum lacunosum‐moleculare of CA1 region of the hippocampus. Finger‐like extensions of the glial processes at both sides of the spine (arrows) isolating these synaptic structures from the surrounding neuropil. s: spine. Adapted from (Derouiche and Frotscher, 1991). (B) Extremely fine PAPs (<100 nm, small arrows) ensheating pre‐ and/or postsynaptic elements (bold arrow in B1 pointing at synaptic cleft); mGluR2/3 (B1) and mGluR5 (B2) are present close to the synapse. Adapted from (Lavialle et al., 2011). (C) Double‐immunogold labeling of Kir4.1 (small particles, arrows) and aquaporin 4 (large particles) in vitreal perisynaptic Müller cell membranes (denoted M) surrounding photoreceptor terminals (Pt). Adapted from (Nagelhus et al., 1999). (D) Double labeling of astrocytic processes demonstrating co‐localization of GLT‐1 (small particles) and GLAST (large particles) (*) in rat hippocampus. S: dendritic spines; t: nerve terminals. Adapted from (Haugeto et al., 1996). Scale bars: 0.5 µm (B), 0.5 µm (C), 0.3 µm (D).