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(A) Effect of L-histidine (Hist, 100 mg/kg, i.p.) on aquaporin-4 (AQP4) protein content in plasma membranes of thioacetamide (TAA)-treated rats. (B) Quantitation of AQP4 protein. Values are mean ± SEM of 5 rats in each group. * vs. control (p < 0.05); ** vs. TAA (p < 0.01).