Table 5.

Diagnostic operating characteristics for CTA plaque thickness measurements and MRA IHIS

Diagnostic accuracy	n	Sensitivity (95% CI)	Specificity (95% CI)	PPV (95% CI)	NPV (95% CI)	Accuracy (95% CI)
Overall	48
Soft (2.4 mm threshold)		91.2 (76.3–98.1)	85.7 (57.2–98.2)	93.9 (79.8–99.3)	80.0 (51.9–95.7)	89.6 (77.3–96.5)
IHIS		67.6 (49.5–82.6)	71.4 (41.9–91.6)	85.2 (66.3–95.8)	47.6 (25.7–70.2)	68.8 (53.7–81.3)
50–69% stenosis	23
Soft (2.2 mm threshold)		91.7 (61.5–99.8)	72.7 (39.0–94.0)	78.6 (49.2–95.3)	88.9 (51.8–99.7)	82.6 (61.2–95.0)
IHIS		75.0 (42.8–94.5)	63.6 (30.8–89.1)	69.2 (38.6–90.9)	70.0 (34.8–93.3)	69.6 (47.1–86.8)
70–99% stenosis	25
Soft (3.5 mm threshold)		81.8 (59.7–94.8)	100.0 (29.2–100.0)	100.0 (81.5–100.0)	42.9 (9.9–81.6)	84.0 (63.9–95.5)
IHIS		63.6 (40.7–82.8)	100.0 (29.2–100.0)	100.0 (76.8–100.0)	27.3 (6.0–61.0)	68.0 (46.5–85.1)
Soft (2.4 mm) and IHIS	36	91.7 (73.0–99.0)	83.3 (51.6–97.9)	91.7 (73.0–99.0)	83.3 (51.6–97.9)	88.9 (73.9–96.9)

All values shown in the table expressed as percentages.