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. Author manuscript; available in PMC: 2016 Jun 1.
Published in final edited form as: Bone. 2015 Feb 25;75:120–127. doi: 10.1016/j.bone.2015.01.021

Figure 1. STO-609 administration stimulates trabecular bone formation in thirty-two week old mice.

Figure 1

(Ai) Representative calcein and alizarin red-labelled sections of proximal tibiae from thirty-two week old mice that were administered saline or STO-609 for six weeks (400× magnification). (Aii) Representative digital polarized images of picrosirius red-stained methyl methacrylamide sections of proximal tibiae from saline or STO-609 treated mice (400× magnification). (B-C) Dynamic histomorphometry analysis of trabecular bone formation in proximal tibiae: mineral apposition rate (MAR) and bone formation rate (BFR). Average values ± standard deviation from saline (n=5) and STO-609 treated (n=8) 32 week old WT mice are shown. Actual p-values are shown.