Table.
Femur mid-diaphysis |
|||||
---|---|---|---|---|---|
WT | Camkk2 −/− | ||||
|
|||||
12W | 32W- Saline |
32W + STO- 609 |
12W | 32W | |
Mediolateral inner diameter (mm) | 1.33 ± 0.05 | 1.27 ± 0.08 | 1.44 ± 0.11 | 1.5 ± 0.1 | 1.35 ± 0.08 |
Mediolateral outer diameter (mm) | 1.84 ± 0.05 | 1.66 ± 0.04 | 1.86 ± 0.12 | 2.0 ± 0.14 | 1.84 ± 0.15 |
Dorsoventral inner diameter (mm) | 0.87 ± 0.04 | 0.78 ± 0.07 | 0.9 ± 0.06 | 1 ± 0.03 | 0.9 ± 0.06 |
Dorsoventral outer diameter (mm) | 1.3 ± 0.07 | 1.2 ± 0.07 | 1.5 ± 0.03 | 1.5 ± 0.03 | 1.34 ± 0.02 |
Crosssectional area moment of inertia (mm4) |
0.157 ± 0.04 | 0.112 ± 0.03*# | 0.155 ± 0.03*@ | 0.232 ± 0.04**~ | 0.17 ± 0.02**~ |
Cortical bone thickness (mm) | 0.46 ± 0.05 | 0.4 ± 0.05 | 0.43 ± 0.04 | 0.5 ± 0.04 | 0.47 ± 0.06 |
- p-value < 0.05;
- p-value <0.01.
Statistical significance is denoted as:
- compared to 12W WT;
- compared to 32W-saline;
- compared to respective age-matched WT cohorts.