Fig. 1.

Inhibiting CX3CR1 results in decreased glomerular volume and FMA in mouse kidneys. (a) Glomerular volume and (b) FMA. (c–f) PAS-stained mouse kidney sections (scale bar, 20 µm): (c) WT non-diabetic mice; (d) Cx3cr1 KO non-diabetic mice; (e) WT diabetic mice; (f) Cx3cr1 KO diabetic mice. Data are mean±SE or images representative of PAS staining in 8–12 mice. ^*p<0.05 vs control Cx3cr1 WT mice; ^†p<0.05 vs diabetic WT mice. Black bars, control; white bars, diabetes. +/+, WT; −/−, Cx3cr1 KO