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. 2015 Oct 29;6(1):e18–e24. doi: 10.1055/s-0035-1566313

Table 3. Obstetrician responses to questions about clinical utilization of expanded NIPT.

Responses n (%)
For which patients do you order the expanded testing option when ordering NIPT? Check all that apply. (n = 12)
 Family history of trisomy 16, trisomy 22, or a microdeletion syndrome 7 (58)
 Ultrasound indicative of trisomy 16, trisomy 22, or a microdeletion syndrome 5 (42)
 Those who request it 6 (50)
 All pregnant patients who pursue NIPT 4 (33)
For those patients for whom you do not order the expanded testing option, what factors influence your decision not to order it? Check all that apply. (n = 12)
 Lack of interest from my patient 3 (25)
 My patient cannot afford it/it is not covered by their insurance 7 (58)
 Not enough published data regarding accuracy 1 (8)
 My professional society(ies) have not published guidelines 1 (8)
 I order this testing for all of my patients 2 (17)
 Other 1 (8)
 No response 2 (17)
If a patient had a positive NIPT expanded testing result, what would be your first recommendation? Please select the best answer. (n = 12)
 I would offer CVS/amniocentesis 3 (25)
 I would refer the patient to a specialist, such as an MFM or genetic counselor 10 (83)
With regard to the NIPT expanded testing option, when do you refer patients to an MFM/genetic counselor? (n = 29)
 Before ordering the test 13 (45)
 Only when patients have a positive result 16 (55)
 I am unsure 2 (7)
What do you tell your patients the accuracy is for the NIPT expanded testing option? (n = 12)
 99–100% 6 (50)
 90–98% 3 (25)
 I am unsure 2 (17)
 No response 1 (8)

Abbreviations: CVS, chorionic villus sampling; MFM, maternal–fetal medicine; NIPT, noninvasive prenatal testing.