Table 3. Obstetrician responses to questions about clinical utilization of expanded NIPT.
Responses | n (%) |
---|---|
For which patients do you order the expanded testing option when ordering NIPT? Check all that apply. (n = 12) | |
Family history of trisomy 16, trisomy 22, or a microdeletion syndrome | 7 (58) |
Ultrasound indicative of trisomy 16, trisomy 22, or a microdeletion syndrome | 5 (42) |
Those who request it | 6 (50) |
All pregnant patients who pursue NIPT | 4 (33) |
For those patients for whom you do not order the expanded testing option, what factors influence your decision not to order it? Check all that apply. (n = 12) | |
Lack of interest from my patient | 3 (25) |
My patient cannot afford it/it is not covered by their insurance | 7 (58) |
Not enough published data regarding accuracy | 1 (8) |
My professional society(ies) have not published guidelines | 1 (8) |
I order this testing for all of my patients | 2 (17) |
Other | 1 (8) |
No response | 2 (17) |
If a patient had a positive NIPT expanded testing result, what would be your first recommendation? Please select the best answer. (n = 12) | |
I would offer CVS/amniocentesis | 3 (25) |
I would refer the patient to a specialist, such as an MFM or genetic counselor | 10 (83) |
With regard to the NIPT expanded testing option, when do you refer patients to an MFM/genetic counselor? (n = 29) | |
Before ordering the test | 13 (45) |
Only when patients have a positive result | 16 (55) |
I am unsure | 2 (7) |
What do you tell your patients the accuracy is for the NIPT expanded testing option? (n = 12) | |
99–100% | 6 (50) |
90–98% | 3 (25) |
I am unsure | 2 (17) |
No response | 1 (8) |
Abbreviations: CVS, chorionic villus sampling; MFM, maternal–fetal medicine; NIPT, noninvasive prenatal testing.