Table 2.

Drug-induced Brugada-like ECG Patterns

I. Antiarrhythmic drugs

1. Na+ channel blockers

Class IC drugs (Flecainide 37, 38, 262–264, Pilsicainide 265, 266, Propafenone 267)

Class IA drugs (Ajmaline 37, 268, Procainamide 37, 46, Disopyramide 31, 46, Cibenzoline 269)

2. Ca2+ channel blockers

Verapamil

II. Antianginal drugs

1. Ca2+ channel blockers

Nifedipine, Diltiazem.

2. Nitrate

Isosorbide dinitrate, Nitroglycerine 270.

3. K+ channel openers

Nicorandil.

III. Psychotropic drugs

1. Tricyclic antidepressants

Amitriptyline271, 272, Nortriptyline 177, Desipramine 175, Clomipramine 176.

2. Tetracyclic antidepressants

Maprotiline 271.

3. Phenothiazine

Perphenazine 271, Cyamemazine., Trifluoperazine272

4. Other antipsychotics

Loxapin 272,

5. Selective serotonin reuptake inhibitors

Fluoxetine 272.

6. Anticonvulsives

Oxcarbazepine 273

IV.Anesthetic and analgesics

1. Bupivacaine274,275

2. Procaine 276

3. Propofol277–279

V. Other drugs

1. Histaminic H1 receptor antagonists

Dimenhydrinate 181.

2. Cocaine intoxication 178, 280

3. Alcohol Intoxication

4. Cannabis 281

5. Ergonovine 182

6. Acetilcholine46, 182

Modified from⁴⁴, with permission