Table 1.
Components of the RNA editing core complex from T. brucei.
| Alternative names for proteins | Gene ID | Proposed function |
|---|---|---|
| MP81/KREPA1 | Tb927.2.2470 | structural, U-insertion subdomain organizer |
| MP63/KREPA2 | Tb927.10.8210 | structural, U-deletion subdomain organizer |
| MP42/KREPA3 | Tb927.8.620 | structural |
| MP24/KREPA4 | Tb927.10.5110 | structural, RNA binding |
| MP19/KREPA5 | Tb927.8.680 | structural |
| MP18/KREPA6 | Tb927.10.5120 | structural, RNA binding |
| REN1/KREN1 | Tb927.1.1690 | insertion site specific endonuclease |
| REN2/KREN2 | Tb927.10.5440 | deletion site specific endonuclease |
| REN3/KREN3 | Tb927.10.5320 | cis-editing site specific endonuclease |
| MP46/KREPB4 | Tb927.11.2990 | structural, heterodimer with endonuclease |
| MP44/KREPB5 | Tb927.11.940 | structural, endonuclease |
| MP49/KREPB6 | Tb927.3.3990 | structural, part of KREN3 module |
| MP47/KREPB7 | Tb927.9.5630 | structural, part of KREN2 module |
| MP41/KREPB8 | Tb927.9.5630 | structural, part of KREN1 module |
| REX1/KREX1 | Tb927.7.1070 | U-specific exonuclease |
| REX2/KREX2 | Tb927.10.3570 | U-specific exonuclease |
| REL1/KREL1 | Tb927.9.4360 | RNA ligase |
| REL2/KREL2 | Tb927.1.3030 | RNA ligase |
| RET2/KRET2 | Tb927.7.1550 | TUTase |
Two alternative nomenclatures are used in the current literature to describe RECC subunits [85;102]. Gene identification numbers are provided according to TriTrypDB 5.0 database release (http://tritrypdb.org/tritrypdb/).