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. Author manuscript; available in PMC: 2016 Aug 1.
Published in final edited form as: Heart Rhythm. 2015 Apr 11;12(8):1852–1866. doi: 10.1016/j.hrthm.2015.04.014

Figure 2.

Figure 2

J wave Syndromes. Schematic depicts our working hypothesis that an outward shift in repolarizing current due to a decrease in sodium or calcium channel currents or an increase in Ito, IK-ATP, IKr or IK-ACh, or other outward currents can give rise to accentuated J waves associated with the BrS, Early Repolarization Syndrome and some forms of IVF. The particular phenotype depends on what part of the heart is principally affected and which ion channels are involved. Accentuation of thee J waves in the right ventricular outflow tract (RVOT) gives rise to BrS, whereas accentuation in the infero-lateral left ventricle (LV) gives rise to ERS.