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. 2016 Jan 20;6(3):404–417. doi: 10.7150/thno.13478

Figure 1.

Figure 1

Schematic diagram of the smart multifunctional nanoplatform (HMPBs-DOX/PFH) for dual-mode imaging and tumor therapy. The fabrication process of HMPBs-DOX/PFH: ① doxorubicin (DOX) loading, ② temperature-sensitive liquid PFH encapsulation. After HIFU exposure, drug release and PFH bubbles generation were observed ③ This versatile nanoplatform can be detected under US and PA for dual-mode guiding and monitoring tumor therapy, as well as enhancing synergistic effect of HIFU ablation and chemotherapeutics.