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Radiation response of B16F10 cells untreated or treated with AGuIX®. The sensitivity enhancement ratio (SER) was calculated as the ratio of cell survival without and with AGuIX® treatment at 2 Gy. Additionally, the percentage enhancement factor at 2 Gy was calculated as 
. DEF is the dose enhancement fraction; SF2 is the survival fraction at 2 Gy.
| ɑ (Gy-1) |
β (Gy-2) |
D50% (Gy) |
SF2 | %EF 2Gy | DEF | SER 2Gy | |
|---|---|---|---|---|---|---|---|
| Control | 0.04 | 0.26 | 4.5 | 0.96 | - | - | |
| 0.6 mg/L AGuIX | 0.26 | 0.022 | 1.8 | 0.46 | 52 % | 1.3 | 2.08 |
