Table 2. Logistic regression analysis of the impact of A-allele SNP on the risk of pancreatic cancer over other GI cancers or no cancer controls.
| Condition | Comparator | Odds ratio and 95% confidence limits (for increase of one copy of A-allele SNP) | P-value |
|---|---|---|---|
| Pancreatic cancer | Other GI cancer (colon/gastric) | 1.90 (1.04–3.43) | 0.0349 |
| Pancreatic cancer | Pennsylvania no cancer control cohort | 2.21 (1.15–4.53) | 0.0214 |
| Pancreatic cancer | NCBI no cancer control cohort | 1.65 (1.01–2.63) | 0.0389 |
| Other GI cancer (colon/gastric) | Pennsylvania no cancer control cohort | 1.17 (0.60–2.27) | 0.643 |
GI, gastrointestinal; NCBI, national center for biotechnology information; SNP, single-nucleotide polymorphism.