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. 2016 Jan 21;7(1):e138. doi: 10.1038/ctg.2015.66

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Copyright © 2016 American College of Gastroenterology

Clinical and Translational Gastroenterology is an open-access journal published by Nature Publishing Group. This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/

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Levels and preferential localization of Hsp60 in control and ethanol-fed mice. (a) Liver sections stained with a monoclonal antibody specific for Hp60. Bar=100 μm for all panels. (b) Histogram showing the percentages of hepatocytes positive to Hsp60. The analysis was conducted in a blind manner (using coded slides with the observer not knowing the source of them). *P<0.001 vs. all other groups (except for 4EtOH); ^ΔP<0.001 vs. 4EtOH; §P<0.05 vs. 4EtOH-P and 12EtOH-P. For the meaning of the abbreviations in a and b, indicating each mouse group, see legend for Figure 1 and Table 1. Con, Control; 4EtOH, ethanol-fed mice for 4 weeks; 8EtOH, ethanol-fed mice for 8 weeks; 12EtOH, ethanol-fed mice for 12 weeks; 4EtOH-P, ethanol and probiotic-fed mice for 4 weeks; 8EtOH-P, ethanol and probiotic-fed mice for 8 weeks; 12EtOH-P, ethanol and probiotic-fed mice for 12 weeks; 8EtOH-4P, ethanol-fed mice for 8 weeks and then given probiotic for 4 weeks; wks, weeks.