Table 6.
Median changes in LENT SOMA aggregate parameter scores for rectum and intestine from baseline to 12 months in patients assessed within 10–14 months
|
Median score at baseline (IQR) |
Median score at 12 months (IQR) |
Median change from baseline to 12 months (IQR) |
Mann-Whitney testUscore | p value | ||||
|---|---|---|---|---|---|---|---|---|
| Sham (n=26) | Hyperbaric oxygen (n=46) | Sham (n=26) | Hyperbaric oxygen (n=46) | Sham (n=26) | Hyperbaric oxygen (n=46) | |||
| Rectum | 6 (5 to 8) | 6 (4 to 8) | 4·5 (2 to 8) | 5 (3 to 8) | −1·5 (−4 to 0) | −1 (−2 to 1) | 1·56 | 0·12 |
| Intestine | 2·5 (1 to 4) | 4 (2 to 5) | 1 (1 to 4) | 2·5 (1 to 4) | 0 (−1 to 1) | 0 (−2 to 0) | −1·30 | 0·20 |
High scores indicate worse symptoms; a negative change indicates a lower score at 12 months, signifying improvement in function. LENT SOMA=Late Effects in Normal Tissues Subjective, Objective, Management and Analytic scale. 46 (55%) patients had grade 1–4 rectal bleeding at baseline as assessed by the LENT SOMA scale.