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. 2015 Aug 14;10(2):321–332. doi: 10.1038/ismej.2015.114

Figure 4.

Figure 4

Antibiotic-induced diabetes is associated with microbial dysbiosis. Communities were profiled in the ileum and colon of control NOD mice and those treated with vancomycin and neomycin by 454 pyrosequencing. (a) Antibiotic-treated mice have less diverse intestinal microbiota. Microbial communities of antibiotic-treated mice are different compared with untreated NOD in the ileum (b; vancomycin P=0.003, neomycin P=0.003) and colon (c; vancomycin P=0.004, neomycin P=0.005). Several microbes are different in abundance in the ileum (d) and colon (e) of antibiotic-treated mice (n=4–8, ND=none detected). *P<0.05 and **P<0.01 by FDR-corrected one way analysis of variance with Tukey's post hoc test.