Fig. 1.
Cellular metabolism. (A) Basal oxygen consumption rate (OCR) of cells treated with 0.5%, 0.25%, or 0.125% beetroot (BR) by volume or control medium for 24 hours. (B) Peak OCR of cells treated as described in the main text. (C) Endogenous proton leak (uncoupling) of cells treated as described in the main text. (D) Basal extracellular acidification rate (ECAR) of cells treated as described in the main text. (E) Peak ECAR of cells treated as described in the main text. (F) Metabolic reliance expressed as the OCR/ECAR ratio of cells treated as described in the main text. Bar graphs are displayed as complete trial area under the curve (AUC). Note. Data are displayed as group mean ± standard deviation. *p < 0.05, **p < 0.01, ***p < 0.001 compared with control. †p < 0.05 between 0.5% and 0.125% BR by volume. ‡p < 0.05 between 0.5% and 0.25% BR by volume.