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. Author manuscript; available in PMC: 2017 Feb 1.
Published in final edited form as: J Rheumatol. 2015 Dec 15;43(2):273–281. doi: 10.3899/jrheum.150179

Figure 4.

Figure 4

Variability in reactivity to CarP, Sa antigen, citrullinated (cit-) fibrinogen, and cit-peptides in the Dartmouth Cohort. A. ACarP(+) samples, have a stronger relationship to cit-fibrinogen reactivity than in (B) AcarP(−) samples (p< 0.0001). There is no relationship between anti-Sa and cit-fibrinogen values either in the ACarP(+) samples (R= -0.08; p= 0.79; n=13) or in the ACarP(−) samples (R= −0.028; p= 0.91; n=18). C. Using a multiplex fluorescent bead array, antibody reactivity to citrullinated (cit-) vimentin 59-78, cit-fibrinogen-α 616-635, cit-fibrinogen-α 39-50, cit-fibrinogen-β 36-52, and cit-α-enolase 5-21 was measured in ACarP Ab(+) (n=14) and ACarP Ab(−) (n=30) samples. Values displayed represent AU/mL for CarP reactivity while the values for the peptides represent mean MFI (median fluorescence intensity) of reactivity to the citrullinated peptide minus the value obtained from native peptide (corrected value).