Table 2.
Unadjusted and Multivariable-Adjusted Association of Adiponectin Levels* with Subclinical Markers of Cardiovascular Disease
| Subclinical CVD Marker | Standardized β-coefficient | P-value |
|---|---|---|
| Left ventricular wall thickness | ||
| Unadjusted | −0.32 | <0.0001 |
| Multivariable-adjusted† | −0.03 | 0.04 |
| Aortic wall thickness | ||
| Unadjusted | −0.08 | 0.0002 |
| Multivariable-adjusted† | 0.03 | 0.19 |
| Left ventricular end-diastolic volume indexed to body surface area | ||
| Unadjusted | 0.07 | 0.001 |
| Multivariable-adjusted† | 0.15 | <0.0001 |
| Left ventricular mass indexed to body surface area | ||
| Unadjusted | −0.19 | <0.0001 |
| Multivariable-adjusted† | 0.03 | 0.10 |
| Liver fat | ||
| Unadjusted | −0.28 | <0.0001 |
| Multivariable-adjusted† | −0.29 | <0.0001 |
| Coronary artery calcium (log-transformed) | ||
| Unadjusted | −0.09 | <0.0001 |
| Multivariable-adjusted† | 0.004 | 0.81 |
*
Adiponectin is modeled per 1-standard deviation of the log-transformed variable
†
Models are adjusted for age, sex, race, hypertension, diabetes, smoking, high-density lipoprotein cholesterol, hyperlipidemia, C-reactive protein level, estimated glomerular filtration rate, and body mass index.