Table 2.
Description Of Change Parameters For Clinical And Medical Variables
| Variable | Change measurement | Subgroup classification |
|---|---|---|
| CD4 count | Crossed a boundary value of 200 cells/μL in either direction |
Stable: CD4 count consistently above or below 200 cells/μL at both visits Change: CD4 count increased or decreased past boundary value of 200 cells/μL between assessments |
| Viral load | Crossed a boundary value of detectable virus (50 copies/μL) |
Stable: consistently undetectable or detectable at both visits Change: viral load at follow-up visit different from baseline visit |
| Illicit substance use |
Urine toxicology test for use of illicit substances |
Stable: consistently positive or negative at each visit Change: status at follow-up visit different from baseline visit |
| Cognitive status |
sRCS |
Stable: sRCS value remained within 90% CI Decline: Bottom 5% sRCS values Improvement: Top 5% sRCS values |
Note. sRCS = standard regression-based change score; CI = confidence interval.