Reference number	24	28	25	31	29	26	30	27
All observational studies
Exposure was assessed at the individual level	√	√	√	√	√	√	√	√
Outcomes were based on objective tests or standard criteria in 90% of study participants	√	√	√	√	√	√	√	√
The authors presented internal comparisons within study participants		√	√	√				√
The authors controlled for potential confounding risk factors in addition to age	√	√		√				√
Prospective cohort studies
Loss to follow-up was independent of exposure
The intensity of search of disease was independent of exposure status				√
Case-control studies
Data were collected in a similar manner for all participants	√	√				√	√	√
The same exclusion criteria were applied to all participants		√				√		√
The selection process for Non-cases was described		√
Samples were collected ≤ 24 hour after the onset of symptoms for all cases				√				√
The study was based on incident cases of disease	√							√
Non cases were persons who would have been excluded if they had developed CAD

CAD: Coronary artery diseases