Fig. 2.
Intercentrosome distance in multinucleates is dependent on MT length. Left panel shows two tetranucleated WT cells ±2.5 μg/ml nocodazole treatment. MTs are in green, nuclei in blue, actin cortex is in red. Arrowheads mark centrosome positions. Right panel quantitates distance between all centrosome pairs in tri-, tetra- and penta-nucleated cells, ±nocodazole treatment. Note that the average distance decreases by at least half after nocodazole-induced MT depolymerization (p values for each comparison are <10−9). Bar 10 μm