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. Author manuscript; available in PMC: 2017 Feb 15.
Published in final edited form as: Bioorg Med Chem. 2015 Dec 17;24(4):578–587. doi: 10.1016/j.bmc.2015.12.024

Table 1.

Experimentally determined inhibitory potencies, radical scavenging activities, and cell viability data for the 20 chalcones. Entries are the averages and standard deviations of at least three independent trials.

compound # IC50 / µM % DPPH
scavenging
% cell
viability
1 inactive 6.7 ± 5 1.7 ± 1
2 inactive 0.2 ± 4 5.9 ± 5
3 inactive −1.4 ± 3 1.4 ± 2
4 inactive −0.6 ± 4 3.0 ± 4
5 290 ± 40 −9.1 ± 10 0
6 inactive −3.0 ± 1 3.9 ± 8
7 53 ± 20 90 ± 1 4.3 ± 6
8 5.3 ± 1 82 ± 9 35 ± 6
9 4.3 ± 1 42 ± 3 28 ± 6
10 27 ± 20 0.5 ± 2 6.9 ± 7
11 35 ± 10 90 ± 9 28 ± 2
12 17 ± 8 91 ± 1 46 ± 6
13 3.0 ± 0.6 77 ± 20 40 ± 2
14 6.5 ± 2 84 ± 3 26 ± 3
15 1.3 ± 0.4 90 ± 2 71 ± 2
16 93 ± 30 70 ± 10 46 ± 2
17 8.6 ± 2 86 ± 1 70 ± 5
18 1.2 ± 0.2 92 ± 3 118 ± 7
19 18 ± 3 57 ± 2 51 ± 3
20 5.5 ± 0.9 82 ± 1 91 ± 6