Table 1.
Experimentally determined inhibitory potencies, radical scavenging activities, and cell viability data for the 20 chalcones. Entries are the averages and standard deviations of at least three independent trials.
compound # | IC50 / µM | % DPPH scavenging |
% cell viability |
---|---|---|---|
1 | inactive | 6.7 ± 5 | 1.7 ± 1 |
2 | inactive | 0.2 ± 4 | 5.9 ± 5 |
3 | inactive | −1.4 ± 3 | 1.4 ± 2 |
4 | inactive | −0.6 ± 4 | 3.0 ± 4 |
5 | 290 ± 40 | −9.1 ± 10 | 0 |
6 | inactive | −3.0 ± 1 | 3.9 ± 8 |
7 | 53 ± 20 | 90 ± 1 | 4.3 ± 6 |
8 | 5.3 ± 1 | 82 ± 9 | 35 ± 6 |
9 | 4.3 ± 1 | 42 ± 3 | 28 ± 6 |
10 | 27 ± 20 | 0.5 ± 2 | 6.9 ± 7 |
11 | 35 ± 10 | 90 ± 9 | 28 ± 2 |
12 | 17 ± 8 | 91 ± 1 | 46 ± 6 |
13 | 3.0 ± 0.6 | 77 ± 20 | 40 ± 2 |
14 | 6.5 ± 2 | 84 ± 3 | 26 ± 3 |
15 | 1.3 ± 0.4 | 90 ± 2 | 71 ± 2 |
16 | 93 ± 30 | 70 ± 10 | 46 ± 2 |
17 | 8.6 ± 2 | 86 ± 1 | 70 ± 5 |
18 | 1.2 ± 0.2 | 92 ± 3 | 118 ± 7 |
19 | 18 ± 3 | 57 ± 2 | 51 ± 3 |
20 | 5.5 ± 0.9 | 82 ± 1 | 91 ± 6 |