Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Feb 3;6:20352. doi: 10.1038/srep20352

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2016, Macmillan Publishers Limited

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

PMC Copyright notice

Adsorption of the ERα antibody with its peptide antigen abolished the neuronal and NFTs immunostaining in the hippocampus (A,B, *denotes landmark vessel on adjacent sections, Scale bar = 50 μm). A sample of breast cancer tissue revealed positive nuclear signal for the antibody as expected (C). The specificity of the antibody was further confirmed as the pia mater and glial cells near the outermost edge of each hippocampal tissue section in all cases was stained as has been previously shown (Scale bar C–F = 20 μm). In addition to glial nuclei staining found in the hippocampus of every case examined (arrowheads, E), occasional neuronal nuclei were found to contain ERα (E, arrows). Many GFAP-lableled astrocytes had ERα nuclear staining (F, GFAP-blue, ERα- brown).