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. 2016 Feb 3;6:20033. doi: 10.1038/srep20033

Figure 5. G-protein is required for 5-HT2A/C receptor mediated reduction of GABA-activated currents.

Figure 5

In the presence of GDP-b-s (500 μM), which was included in the pipette solution, 5-HT (a) and DOI (b) failed to attenuate the GABA currents. (c), Quantification data showing no effect of 5-HT (n = 6) and DOI (n = 6) on GABA current after blocking the activation of G-protein.