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. 2016 Feb 3;6:20033. doi: 10.1038/srep20033

Figure 7. Phospholipase C and protein kinase C act as downstream signaling of 5-HT2A/C receptors.

Figure 7

Inclusion of U-73122 (5 μM, n = 6, (a) GF 109203X (2.5 μM, n = 5, (b) in the pipette solution prevented the modulatory effect of DOI on GABA currents, but forskolin (10 μM, n = 5, c) failed to achieve the occluding effect. (c), Quantification data showing that activation of PLC-PKC pathway caused the reduction of GABA currents.