Table 1. Baseline characteristics and clinical features of anaphylaxis patients according to the development of hypotension.
| Variables | no hypotension (n = 300) | hypotension (n = 40) | P Value |
|---|---|---|---|
| Demographic factor | |||
| Age, years | 46.0 ± 15.5 | 42.7 ± 13.9 | 0.208 |
| Male sex | 145 (48.3) | 18 (45.0) | 0.738 |
| Comorbidity | |||
| Hypertension | 39 (13.0) | 5 (12.5) | 1.000 |
| Diabetes mellitus | 11 (3.7) | 0 (0.0) | 0.374 |
| Cardiac disease | 14 (4.7) | 3 (7.5) | 0.705 |
| Neoplasm | 29 (9.7) | 5 (12.5) | 0.781 |
| CKD | 2 (0.7) | 1 (2.5) | 0.314 |
| Bronchial asthma | 13 (4.3) | 1 (2.5) | 1.000 |
| History of allergy | 109 (36.3) | 13 (32.5) | 0.727 |
| History of anaphylaxis | 25 (8.3) | 3 (7.5) | 1.000 |
| Symptoms and Signs | |||
| Mucocutaneous | 261 (87.0) | 34 (85.0) | 0.803 |
| Cardiovascular | 110 (36.7) | 17 (42.5) | 0.490 |
| Pulmonary | 203 (67.7) | 24 (60.0) | 0.373 |
| Gastrointestinal | 93 (31.0) | 19 (47.5) | 0.048 |
| Neurologic | 63 (21.0) | 21 (52.5) | 0.000 |
| Trigger | |||
| Drug | 75 (25.0) | 20 (50.0) | 0.001 |
| Contrast media | 48 (16.0) | 3 (7.5) | 0.236 |
| Food | 106 (35.3) | 10 (25.0) | 0.218 |
| Insect venom | 18 (6.0) | 2 (5.0) | 1.000 |
| Contact | 4 (1.3) | 1 (2.5) | 0.467 |
| Idiopathic | 47 (15.7) | 4 (10.0) | 0.480 |
| Severe on severity Gradea | 48 (16.0) | 9 (22.5) | 0.365 |
| Initial vital signs | |||
| Systolic BP, mmHg | 129.3 ± 23.4 | 114.1 ± 24.7 | 0.000 |
| Diastolic BP, mmHg | 81.1 ± 17.3 | 70.3 ± 27.7 | 0.020 |
| Heart rate, beats/min | 90.9 ± 21.4 | 88.8 ± 23.2 | 0.562 |
| Respiratory rate, breaths/min | 21.6 ± 3.6 | 22.9 ± 5.7 | 0.170 |
| Oxygen saturation, % | 97.5 ± 2.6 | 96.3 ± 3.6 | 0.052 |
CKD: chronic kidney disease; BP: blood presssure.
Values are expressed as mean ± SD, n (%).
aSevere was defined as cyanosis or SpO2 ≤ 92%, hypotension (systolic BP < 90 mm Hg), confusion, collapse, loss of consciousness, or incontinence at admission.