Table 3. Concentration of ADP and its metabolites in tissues of swine (n = 4) dosed ³ H-ADP for 7 days.

Tissue	Time(d)	Concentration (mg/kg)
		A0	A1	A2	A3	A4	A5	A6	A7	A8	A9	A10	A11
Liver	0.25	7.60 ± 1.04	4.62 ± 0.85	2.44 ± 0.48	0.94 ± 0.17	0.32 ± 0.03	0.43 ± 0.04	0.36 ± 0.04	0.79 ± 0.17	0.02 ± 0.00	0.19 ± 0.02	0.32 ± 0.03	0.78 ± 0.08
	1	3.01 ± 0.90	1.65 ± 0.33	0.84 ± 0.11	ND	0.27 ± 0.04	0.26 ± 0.04	ND	0.45 ± 0.09	ND	ND	ND	0.22 ± 0.03
	3	1.32 ± 0.27	0.64 ± 0.11	0.31 ± 0.08	ND	ND	ND	ND	ND	ND	ND	ND	ND
	7	0.82 ± 0.14	ND	ND	ND	ND	ND	ND	ND	ND	ND	ND	ND
	14	0.24 ± 0.05	ND	ND	ND	ND	ND	ND	ND	ND	ND	ND	ND
Kidney	0.25	19.02 ± 8.81	15.36 ± 5.3	6.36 ± 1.04	ND	0.52 ± 0.08	0.71 ± 0.11	0.69 ± 0.10	ND	ND	0.85 ± 0.13	0.47 ± 0.07	1.25 ± 0.18
	1	4.16 ± 2.00	3.43 ± 1.25	1.30 ± 0.40	ND	0.48 ± 0.26	0.27 ± 0.15	0.06 ± 0.03	ND	ND	0.30 ± 0.16	0.02 ± 0.01	ND
	3	1.08 ± 0.22	0.16 ± 0.04	0.02 ± 0.01	ND	ND	ND	ND	ND	ND	ND	ND	ND
	7	0.36 ± 0.09	0.02 ± 0.00	ND	ND	ND	ND	ND	ND	ND	ND	ND	ND
	14	0.11 ± 0.02	ND	ND	ND	ND	ND	ND	ND	ND	ND	ND	ND
Muscle	0.25	1.49 ± 0.39	0.85 ± 0.25	0.16 ± 0.04	ND	ND	ND	ND	ND	ND	ND	ND	ND
	1	0.89 ± 0.22	0.15 ± 0.04	0.05 ± 0.01	ND	ND	ND	ND	ND	ND	ND	ND	ND
	3	0.38 ± 0.09	0.05 ± 0.01	ND	ND	ND	ND	ND	ND	ND	ND	ND	ND
	7	0.07 ± 0.01	ND	ND	ND	ND	ND	ND	ND	ND	ND	ND	ND
	14	ND	ND	ND	ND	ND	ND	ND	ND	ND	ND	ND	ND
Fat	0.25	1.27 ± 0.43	0.30 ± 0.07	0.07 ± 0.01	ND	ND	ND	ND	ND	ND	ND	ND	ND
	1	0.51 ± 0.12	0.06 ± 0.01	ND	ND	ND	ND	ND	ND	ND	ND	ND	ND
	3	0.33 ± 0.07	ND	ND	ND	ND	ND	ND	ND	ND	ND	ND	ND
	7	0.15 ± 0.03	ND	ND	ND	ND	ND	ND	ND	ND	ND	ND	ND
	14	ND	ND	ND	ND	ND	ND	ND	ND	ND	ND	ND	ND

ND: Data was not detected.