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. 2016 Feb 3;6:20223. doi: 10.1038/srep20223

Figure 6. miR-223 prevents AHR/ARNT-induced Notch3 upregulation.

Figure 6

(a) Notch3 mRNA levels in THP-1 cells expressing control (mock) or pre-miR-223 stimulated with BaP or vehicle. Data shown as mean ± SEM of RQ values (triplicates) from three independent experiments. (b) Linear regression analysis of CYP1B1 and Notch3 RQ values in RA and OA samples (n = 10). (c) Proposed model of miR-223 regulation in macrophages; miR-223 activity in RA macrophages indicated in red. *p < 0.05, **p < 0.01, ***p < 0.001, Mann-Whitney U-test.