Table 1.

Top 20 up‐ and downregulated gene transcripts in MDDCs transfected with miR‐650 pre‐miR

Gene symbol	Gene description	FC
Downregulated transcripts
CXCL10	Chemokine (C−X−C motif) ligand 10	−1.84
IFIT2	IFN‐induced protein with tetratricopeptide repeats 2	−1.50
GCH1	GTP cyclohydrolase 1 (dopa‐responsive dystonia)	−1.46
CCL8	chemokine (C−C motif) ligand 8	−1.41
FCGR1A|FCGR1B	Fc fragment of IgG, high affinity Ia and Ib, receptor (CD64)	−1.39
BIRC3	Baculoviral IAP repeat‐containing 3	−1.38
PDCD4	Programmed cell death 4 (neoplastic transformation inhibitor)	−1.35
INDO	Indoleamine‐pyrrole 2,3 dioxygenase	−1.35
LTA4H	Leukotriene A4 hydrolase	−1.33
PLXNC1	Plexin C1	−1.32
GBP5	Guanylate‐binding protein 5	−1.32
CCL5	Chemokine (C−C motif) ligand 5	−1.32
COP1	Caspase‐1 dominant‐negative inhibitor pseudo‐ICE	−1.31
RNF170	ring finger protein 170	−1.31
GBP3	Guanylate binding protein 3	−1.30
GBP4	Guanylate binding protein 4	−1.30
OMA1|DAB1	OMA1 homolog, zinc metallopeptidase | disabled homolog 1	−1.29
CASP1	Caspase 1, apoptosis‐related cysteine peptidase	−1.29
SLC39A8	Solute carrier family 39 (zinc transporter), member 8	−1.29
OAT	Ornithine aminotransferase (gyrate atrophy)	−1.29
Upregulated transcripts
OR52K3P	Olfactory receptor, family 52, subfamily K, member 3	1.33
STAC	SH3 and cysteine‐rich domain	1.26
MOBKL2B	Mps one binder kinase activator‐like 2B (yeast, MOB1)	1.22
RUNX1	Runt‐related transcription factor 1	1.22
C17orf68	Chromosome 17 open reading frame 68	1.21
FAM83G	Family with sequence similarity 83, member G	1.20

MDDCs were transfected with pre‐miR‐650 or scramble control for 24 h and microarray analysis was performed using the Affymetrix GeneChip Human Gene 1.0 ST array. Fold changes (FC) are shown relative to scramble control.