Table 1.
Baseline demographics (FAS)
| Parameter | Capsaicin 8% patch (n = 282) | Pregabalin (n = 277) |
|---|---|---|
| Gender, (n, %) | ||
| Male | 123 (43.6) | 122 (44.0) |
| Female | 159 (56.4) | 155 (56.0) |
| Ethnicity (n, %) | ||
| Caucasian | 278 (98.5) | 276 (99.6) |
| Asian | 1 (0.4) | 1 (0.4) |
| Other | 3 (1.1) | 0 (0.0) |
| Age (years) | ||
| Mean (SD) | 55.4 (14.0) | 56.3 (13.5) |
| Min–Max | 20–81 | 19–80 |
| Body Mass Index (kg/m2) | ||
| Mean (SD) | 27.0 (5.1) | 27.4 (5.2) |
| Min–Max | 17–58 | 18–49 |
| NPRS average score | ||
| Mean (SD) | 6.5 (1.2) | 6.7 (1.2) |
| <7 | 162 (57.4) | 150 (54.2) |
| ≥7 | 120 (42.6) | 127 (45.8) |
| Duration of neuropathic pain (years) | ||
| Mean (SD) | 2.58 (4.3) | 2.12 (2.9) |
| Min–Max | 0.0–36.2 | 0.0–19.3 |
| Type of neuropathic pain (n, %) | ||
| Post‐herpetic neuralgia | 63 (22.3) | 73 (26.3) |
| Post‐traumatic nerve injury | 146 (51.8) | 137 (49.5) |
| Non‐diabetic painful peripheral polyneuropathy | 73 (25.9) | 67 (24.2) |
| Time since diagnosis | ||
| <6 months | 69 (24.5) | 63 (22.7) |
| ≥6 months to ≤1 year | 61 (21.6) | 7 (27.8) |
| >1 year to ≤2 years | 60 (21.3) | 48 (17.3) |
| >2 years to ≤10 years | 76 (26.9) | 80 (28.9) |
| >10 years | 16 (5.7) | 9 (3.2) |
| Pain grading | ||
| Probable neuropathic pain | 154 (54.6) | 149 (53.8) |
| Definite neuropathic pain | 128 (45.4) | 128 (46.2) |
| Previous use of pregabalin/gabapentin | ||
| No | 224 (79.4) | 210 (75.8) |
| Yes | 58 (20.6) | 67 (24.2) |
FAS: Full analysis set; NPRS: Numeric Pain Rating Scale.