Table 2. Changes in the metabolite concentrations in the upper non-inoculated leaves following mock inoculation and PVY inoculation.

Metabolic pathway	Metabolite	Time post infection (dpi)
		3		6
		N:mock	NTN:mock	N:mock	NTN:mock
Amino-acid synthesis	Valine	-0.12	-0.44	0.72*	1.26*
	Isoleucine	-0.45	-1.66	2.12	2.52*
	Shikimate	0.37**	0.37*	0.09	0.36
	Citramalate	0.23	0.06	-0.39	-0.45*
TCA cycle	2-Oxoglutarate	0.02	-0.46	2.24**	2.18**
	Malate	0.09	0.03	-0.34	-0.65*
	Citrate	0.4	0.5	0.4	0.8*
ROS scavengers	Lyxonate	-0.12	-0.12	1.37**	1.41**
	Dehydroascorbate	0.61	0.83*	-0.36	-0.67
	Inositol	0.2	0.25	-0.68*	-0.35
Phenylpropanoid	Chlorogenate-cis	0.26	-0.06	2.64**	2.76**
	5-Caffeoylquinate	0.19	-0.72	3.26	3.23*
	Chlorogenate-trans	0.39	0.19	2.01**	2.1**
	4-Caffeoylquinate-cis	0.25	-0.12	2.7**	2.81**

The responses in the leaves to inoculation with PVY^N and PVY^NTN are compared to the mock inoculation (N:mock, NTN:mock, respectively). The log2 ratios of the metabolite concentrations at the different times (i.e., 3, 6 dpi) are shown. The corresponding metabolic pathways were assigned. The statistical significances of the changes in metabolite levels were evaluated (t-tests).

*, p <0.05;

**, p <0.01.