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. 2012 May;40(5):856–864. doi: 10.1124/dmd.111.043828

Fig. 4.

Fig. 4

Model of the locations of the amino acid exchanges as a result of SNPs identified in the hAOX1 gene. Model with program MacPyMOL using bovine XDH (Protein Data Bank code 1FO4): A, Arg793 (Arg802 in human AOX1); B, Arg912 (Arg921 in human AOX1); C, Ser1126 (Asn1135 in human AOX1); D, Asn1288 (His1297 in human AOX1). The amino acid that is affected by the SNPs is marked in red. The cofactors (Moco, FeS clusters, and FAD) are shown in stick representations. The overall (α)2 structure is labeled in light gray for one subunit and in dark gray for the other subunit of the homodimer.