Table 2.
Comparison of urinary oxidative DNA damage levels and plasma antioxidant defense status between control subjects and BCC patients.
| Parameters | Controls (n = 24) | Cases (n = 24) | |||
|---|---|---|---|---|---|
| Before surgery | 1 month after surgery | Before surgery | 1 month after surgery | 6 months after surgery | |
| 8-oxo-dGuo (ng/mg creatinine) | 61.92 ± 17.35 | 71.51 ± 16.68 | 110.08 ± 30.09∗∗∗ | 106.65 ± 26.17∗∗∗ | 64.44 ± 19.02### |
| CAT (unit/mg protein) | 4.38 ± 0.80 | 3.96 ± 0.68 | 2.55 ± 0.43∗∗∗ | 4.34 ± 1.13### | |
| GPx (unit/mg protein) | 0.77 ± 0.20 | 0.77 ± 0.21 | 0.42 ± 0.13∗∗∗ | 0.75 ± 0.11### | |
| NQO1 (µmole DCPIP reduced/min/mg protein) | 928.25 ± 203.20 | 977.87 ± 184.54 | 708.53 ± 112.66∗∗∗ | 1010.30 ± 281.00### | |
| Total SOD (unit/mg protein) | 0.02 ± 0.01 | 0.02 ± 0.00 | 0.04 ± 0.01∗∗∗ | 0.04 ± 0.01∗∗∗ | |
| GSH (µmol/mg protein) | 152.19 ± 44.88 | 156.92 ± 40.41 | 235.76 ± 42.75∗∗∗ | 220.93 ± 52.44∗∗∗ | |
Results were expressed as mean ± standard deviation (SD).
∗∗∗ P < 0.001 compared to control, before surgery.
### P < 0.001 compared to case, before surgery.