Table 3.
Expressions of oxidative DNA damage, DNA repair enzyme, and antioxidant proteins in skin tissues of control subjects and BCC patients by IRS.
| Parameters | Controls (n = 24) | Cases (n = 24) | |
|---|---|---|---|
| Epidermis | BCC | Adjacent epidermis | |
| 8-oxo-dGuo | 2.30 ± 0.67 | 2.88 ± 0.30∗∗∗ | 2.27 ± 0.72### |
| hOGG1 | 2.56 ± 0.47 | 1.77 ± 0.40∗∗∗ | 2.53 ± 0.47### |
| CAT | 1.79 ± 0.63 | 1.18 ± 0.74∗ | 2.00 ± 0.48### |
| GCLC | 2.17 ± 0.57 | 1.59 ± 0.56∗ | 2.70 ± 0.45∗,### |
| GPx | 2.02 ± 0.37 | 1.24 ± 0.51∗∗∗ | 1.73 ± 0.41## |
| Nrf2 | 2.40 ± 0.57 | 1.53 ± 0.47∗∗∗ | 2.33 ± 0.44### |
| MnSOD | 1.95 ± 0.53 | 1.41 ± 0.65∗ | 2.60 ± 0.46∗∗,### |
Results were expressed as mean ± standard deviation (SD).
∗ P < 0.05, ∗∗ P < 0.01, ∗∗∗ P < 0.001 compared to epidermis of control.
## P < 0.01, ### P < 0.001 compared to BCC lesion.