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. 2016 Jan 14;2016:8612190. doi: 10.1155/2016/8612190

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Copyright © 2016 Jinyun Pu et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Effects of Huai Qi Huang (HQH) on zinc-finger E-box binding homeobox ZEB1 and ZEB2 mRNA levels in the obstructed kidneys of UUO rats and NRK-52E cells stimulated with transforming growth factor-β1 (TGF-β1). (a and b) Representative RT-PCR bands and graphic presentation showed levels of ZEB1 and ZEB2 mRNA in obstructed kidneys on day 14 after obstruction. ^∗ p < 0.05 versus vehicle-treated UUO rats on the same day after obstruction. Five rats in each dosage group. The bars show mean ± SEM. (c and d) The relative abundance of ZEB1 and ZEB2 mRNA induced by 10 ng/mL TGF-β1 treatment for 3 h in NRK-52E cells. ^∗ p < 0.05 versus positive control group with the TGF-β1 group at the same time point. All experiments were repeated for three times. The bars showed mean ± SEM.