Table 12.
ATA risk | Study | NED, % | Biochemical incomplete, %b | Structural incomplete, %c |
---|---|---|---|---|
Low | Tuttle et al. (538) | 86 | 11 | 3 |
Castagna et al. (542) | 91 | NDa | NDa | |
Vaisman et al. (539) | 88 | 10 | 2 | |
Pitoia et al. (543) | 78 | 15 | 7 | |
Intermediatea | Tuttle et al. (538) | 57 | 22 | 21 |
Vaisman et al. (539) | 63 | 16 | 21 | |
Pitoia et al. (543) | 52 | 14 | 34 | |
High | Tuttle et al. (538) | 14 | 14 | 72 |
Vaisman et al. (539) | 16 | 12 | 72 | |
Pitoia et al. (543) | 31 | 13 | 56 |
Because the ATA intermediate- and high-risk groups were merged into a single “high-risk” group in the series by Castagna et al. (542), risk of persistent/recurrent disease for these subgroups is not presented.
Proportion of patients with a biochemical incomplete response. Definition: suppressed Tg >1 ng/mL, TSH-stimulated Tg >10 ng/mL, or rising anti-Tg antibody levels in the absence of structural disease.
Proportion of patients with persistent/recurrent disease that is structural. Definition: structural disease that is either biopsy-proven or highly suspicious for disease with or without abnormal serum Tg.
ND, not determined.