Table 1.
Basic clinical data and kidney function parameters depending on CKD stage in the investigated group of 65 patients.
| Parameter | CKD stage | p value | |||
|---|---|---|---|---|---|
| 1 + 2 (n = 11) |
3 (n = 18) |
4 (n = 14) |
5 (n = 22) |
||
| Age (years) | 10.51 (5.04; 16.08) |
11.33 (5.15; 16.33) |
12.01 (8.70; 15.99) |
11.61 (8.51; 15.20) |
0.820 |
|
| |||||
| Height (z-score)∗ | 0.078 (−0.300; 0.569) |
−0.716 (−2.303; 0.060) |
−0.868 (−1.484; −0.210) |
−1.495 (−3.444; −0.130) |
0.013 |
|
| |||||
| Body mass (z-score)∗∗ | −0.015 (−0.409; 0.419) |
−0.980 (−1.635; 0.009) |
−0.464 (−1.054; 0.228) |
−1.587 (−3.714; −0.828) |
0.002 |
|
| |||||
| BMI (kg/m2) | 16.5 (15.8; 22.1) |
16.6 (14.7; 19.5) |
18.1 (16.0; 20.4) |
15.9 (14.5; 17.2) |
0.224 |
|
| |||||
| BMI (z-score)∗∗∗ | 0.316 (−0.318; 0.712) |
−0.779 (−1.636; 0.433) |
0.079 (−0.638; 0.712) |
−1.252 (−1.599; −0.621) |
0.020 |
|
| |||||
| Creatinine (µmol/L)∗∗∗∗ | 69.3 (34.0; 93.8) |
113.8 (95.0; 146.4) |
274.9 (203.8; 311.9) |
501.8 (414.3; 869.0) |
<0.001 |
|
| |||||
| Cystatin C (mg/L)∗∗∗∗ | 0.86 (0.68; 1.23) |
1.45 (1.17; 1.86) |
2.6 (2.23; 3.01) |
4.81 (4.14; 6.53) |
<0.001 |
|
| |||||
| eGFR Filler∗∗∗∗(mL/min/1.73 m2) | 109.46 (72.62; 141.28) |
60.13 (45.64; 76.81) |
29.49 (26.19; 36.49) |
14.77 (9.78; 18.43) |
<0.001 |
Values presented as median (25th–75th percentile).
BMI—body mass index; eGFR—estimated glomerular filtration rate.
∗Statistically significant differences between stages 1 + 2 and 4, 1 + 2 and 5.
∗∗Statistically significant differences between stages 1 + 2 and 3, 1 + 2 and 5, 4 and 5.
∗∗∗Statistically significant differences between stages 4 and 5.
∗∗∗∗Statistically significant differences between all stages.