Table 3.
Pathological parameters.
| Variable | N (%) |
|---|---|
| ypT stage | |
| pT0-1 | 38 (22.8) |
| pT2–4 | 129 (77.2) |
| ypN stage | |
| pN0 | 110 (65.9) |
| pN1-2 | 57 (34.1) |
| Pathological stage | |
| 0 | 58 (34.7) |
| II | 58 (34.7) |
| III | 51 (30.5) |
| T downstaging | |
| Yes | 67 (40.1) |
| No | 100 (59.9) |
| Pathological TNM downstaging | |
| Yes | 95 (56.9) |
| No | 72 (43.1) |
| CRM distance | |
| >2 mm | 159 (95.2) |
| ≤2 and >1 mm | 8 (4.8) |
| Mandard TRG | |
| TRG1-2 (good responders) | 85 (50.9) |
| TRG3–5 (bad responders) | 82 (49.1) |
| Other characteristics of resected specimen | |
| Grade | |
| 0 | 32 (19.2) |
| 1 | 31 (18.6) |
| 2 | 98 (58.7) |
| 3 | 6 (3.6) |
| Mucinous presence | |
| Yes | 41 (24.5) |
| No | 126 (75.4) |
| Inflammatory infiltrate | |
| Scarce | 60 (35.9) |
| Moderated | 75 (44.9) |
| Marked | 28 (16.8) |
| Missing | 4 (2.4) |
| Desmoplastic reaction | |
| Scarce | 45 (26.9) |
| Moderated | 64 (38.3) |
| Marked | 51 (30.5) |
| Missing | 7 (4.2) |
| Necrosis grade | |
| Scarce | 27 (16.2) |
| Moderated | 38 (22.8) |
| Marked | 99 (59.3) |
| Missing | 3 (1.8) |
| Mitosis number | |
| ≤9.5 | 73 (43.7) |
| >9.5 | 68 (40.7) |
| Missing | 26 (15.6) |
| Lymphatic permeation | |
| No | 100 (59.9) |
| Yes | 67 (40.1) |
| Vascular permeation | |
| No | 142 (85) |
| Yes | 25 (15) |
| Perineural permeation | |
| No | 96 (57.5) |
| Yes | 71 (42.5) |
| Distal margin | |
| ≥2 cm | 108 (65.7) |
| <2 cm and ≥1 cm | 59 (35.3) |