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Study of serum atherogenicity in cellular assay. Four patients with atherosclerosis were given water extracts of 8 g of hawthorn berries or 3 g St. John's wort herb. Blood samples were collected before treatment and after 2, 4, and 8 hours and blood serum was added to cultured primary subendothelial intimal cells. Serum atherogenicity was measured as the increase of cholesterol content in cultured cells after 24 h.
