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. 2016 Feb 3;11(2):e0148189. doi: 10.1371/journal.pone.0148189

Table 2. Association between inflammatory biomarkers and atrial fibrillation diagnosed by ECG.

Unadjusted OR P-value Adjusted OR P-value
ECG diagnosed AF at baseline
hs-CRP 1.15 (0.91–1.46) 0.24 1.12 (0.86–1.45) 0.40
Fibrinogen 1.12 (0.89–1.42) 0.33 1.06 (0.82–1.37) 0.66
TNF-α 1.22 (0.83–1.81) 0.31 1.01 (0.64–1.60) 0.9
IL-6 1.70 (1.36–2.12) <0.0001 1.61 (1.21–2.14) 0.001
New-onset atrial fibrillation
hs-CRP 1.16 (1.00–1.35) 0.049 1.13 (0.96–1.33) 0.13
Fibrinogen 1.09 (0.93–1.27) 0.28 1.01 (0.86–1.18) 0.9
TNF-α 1.15 (0.89–1.48) 0.29 0.97 (0.73–1.28) 0.82
IL-6 1.37 (1.16–1.63) 0.0007 1.25 (1.02–1.53) 0.03

Adjusted for age, sex, race, body mass index, diabetes mellitus, smoking, history of CVD, echocardiographic parameters, SBP, eGFR, and use of Angiotensin converting enzyme inhibitor/Angiotensin receptor blocker [ACEi/ARB], antiplatelet agents, beta-blocker, calcium channel-blocker, diuretic, insulin, aspirin, and statins, and UACR and potassium.