Table 2. Association between inflammatory biomarkers and atrial fibrillation diagnosed by ECG.
Unadjusted OR | P-value | Adjusted OR† | P-value | |
---|---|---|---|---|
ECG diagnosed AF at baseline | ||||
hs-CRP | 1.15 (0.91–1.46) | 0.24 | 1.12 (0.86–1.45) | 0.40 |
Fibrinogen | 1.12 (0.89–1.42) | 0.33 | 1.06 (0.82–1.37) | 0.66 |
TNF-α | 1.22 (0.83–1.81) | 0.31 | 1.01 (0.64–1.60) | 0.9 |
IL-6 | 1.70 (1.36–2.12) | <0.0001 | 1.61 (1.21–2.14) | 0.001 |
New-onset atrial fibrillation | ||||
hs-CRP | 1.16 (1.00–1.35) | 0.049 | 1.13 (0.96–1.33) | 0.13 |
Fibrinogen | 1.09 (0.93–1.27) | 0.28 | 1.01 (0.86–1.18) | 0.9 |
TNF-α | 1.15 (0.89–1.48) | 0.29 | 0.97 (0.73–1.28) | 0.82 |
IL-6 | 1.37 (1.16–1.63) | 0.0007 | 1.25 (1.02–1.53) | 0.03 |
† Adjusted for age, sex, race, body mass index, diabetes mellitus, smoking, history of CVD, echocardiographic parameters, SBP, eGFR, and use of Angiotensin converting enzyme inhibitor/Angiotensin receptor blocker [ACEi/ARB], antiplatelet agents, beta-blocker, calcium channel-blocker, diuretic, insulin, aspirin, and statins, and UACR and potassium.