Table 3. Bootstrapped multivariate regression analysis for fatigue (FA), nausea and vomiting (NV), appetite loss (AP) and pain (PA).
FA | NV | AP | PA | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Coeff | 95% CI | p | Coeff | 95% CI | p | Coeff | 95% CI | p | Coeff | 95% CI | p | |
Intercept | 19.75 | (5.80; 33.70) | 0.006 | 7.48 | (-1.83; 16.79) | 0.12 | 18.59 | (0.69; 36.50) | 0.04 | 26.21 | (10.17; 42.24) | 0.001 |
Baseline | 0.65 | (-0.46; -0.05) | <0.001 | 0.47 | (0.36; 0.58) | <0.001 | 0.56 | (0.49; 0.63) | <0.001 | 0.63 | (0.56; 0.60) | <0.001 |
Age | -0.25 | (-046; -0.05) | 0.02 | -0.17 | (-0.32; -0.02) | 0.03 | -0.25 | (-0.50; 0.001) | 0.05 | -0.33 | (-0.55; -0.10) | 0.004 |
Women | 1.40 | (-2.03; 4.83) | 0.42 | 1.61 | (-0.82; 4.04) | 0.19 | 1.92 | (-2.57; 6.42) | 0.40 | 1.79 | (-2.15; 5.74) | 0.37 |
Cancer | 5.88 | (0.43; 11.35) | 0.04 | 3.35 | (-0.43; 7.13) | 0.08 | 10.06 | (2.95; 17.17) | 0.006 | -0.89 | (-7.71; 5.93) | 0.80 |
Duration of symptom (weeks) | 0.04 | (-0.06; 0.14) | 0.46 | 0.001 | (-0.06; 0.06) | 0.99 | 0.11 | (-0.02; 0.25) | 0.10 | -0.01 | (-0.12; 0.11) | 0.94 |
Previous cancer in patient | -0.71 | (-8.05; 6.62) | 0.85 | -0.59 | (-4.91; 3.73) | 0.78 | 5.52 | (-4.21; 15.25) | 0.27 | -4.83 | (-12.79; 3.12) | 0.23 |
Co-morbidity | ||||||||||||
0 | 1 | 1 | 1 | 1 | ||||||||
1 | 4.11 | (-0.24; 8.46) | 0.06 | 3.27 | (0.37; 6.16) | 0.03 | 3.39 | (-2.36; 9.14) | 0.25 | 9.23 | (3.91; 14.55) | 0.001 |
≥2 | 8.97 | (3.66; 14.28) | 0.001 | 4.64 | (1.38; 7.89) | 0.005 | 4.53 | (-2.33; 11.39) | 0.20 | 8.34 | (2.51; 14.18) | 0.005 |
Marital status | ||||||||||||
Married/Co-inhabitant | 1 | 1 | 1 | 1 | ||||||||
Separated/divorced | 0.49 | (-5.58; 6.57) | 0.87 | 4.18 | (-1.25; 9.61) | 0.13 | 2.40 | (-5.79; 10.60) | 0.57 | 3.05 | (-3.55; 9.65) | 0.37 |
Widow/widower | 0.77 | (-5.98; 7.52) | 0.82 | -0.95 | (-5.63; 3.74) | 0.69 | 1.76 | (-5.52; 9.03) | 0.64 | -2.19 | (-9.59; 5.21) | 0.56 |
Unmarried/single | -6.60 | (-12.71; -0.49) | 0.03 | -1.35 | (-5.28; 2.57) | 0.50 | -3.78 | (-12.85; 5.29) | 0.42 | -4.81 | (-12.27; 2.65) | 0.21 |
Education | ||||||||||||
Basic school/high school | 1 | 1 | 1 | 1 | ||||||||
Vocational training (10–12 years) | -0.36 | (-5.08; 4.36) | 0.88 | -1.68 | (-4.87; 1.49) | 0.30 | -0.38 | (-6.84; 6.09) | 0.91 | 1.72 | (-4.06; 7.49) | 0.56 |
Medium academic/trade (<15 years) | -2.84 | (-7.77; 2.09) | 0.26 | -0.84 | (-3.94; 2.27) | 0.60 | -3.64 | (-9.88; 2.60) | 0.25 | 1.46 | (-4.51; 7.42) | 0.63 |
Academic/university level (>15 years) | -3.15 | (-9.01; 2.69) | 0.29 | 0.18 | (-3.74; 4.10) | 0.92 | -4.22 | (-11.85; 3.41) | 0.28 | -1.44 | (-8.62; 5.75) | 0.70 |
Occupation | ||||||||||||
Employed | 1 | 1 | 1 | 1 | ||||||||
Unemployed | 9.91 | (0.84; 18.98) | 0.03 | 2.90 | (-6.31; 12.11) | 0.54 | 1.82 | (-13.73; 17.37) | 0.82 | 6.20 | (-4.55; 16.94) | 0.26 |
Retired/disability/early retirement | 1.56 | (-3.60; 6.73) | 0.55 | 3.78 | (0.05; 7.51) | 0.05 | 4.94 | (-1.31; 11.19) | 0.12 | 1.65 | (-4.59; 7.88) | 0.61 |
Follow-up after diagnosis | -2.02 | (-6.14; 2.11) | 0.34 | -1.38 | (-4.52; 4.04) | 0.19 | -3.90 | (-9.81; 2.02) | 0.20 | -4.54 | (-9.74; 0.67) | 0.09 |