Table 1. Infection status of dogs vaccinated with attenuated mutant Ech_0660.
| Days Post Vaccination | ||||||||
|---|---|---|---|---|---|---|---|---|
| 0 | 3 | 8 | 11 | 14 | 21 | 28 | 31 | |
| Ech_0660_1a | - | - | - | - | - | - | - | - |
| Ech_0660_2 | - | - | - | - | - | - | - | - |
| Ech_0660_3 | - | cb | - | - | - | - | - | - |
| Ech_0660_4 | - | - | - | - | - | - | - | - |
| Ech_0660_5 | - | - | - | - | - | - | - | - |
| Ech_0660_6 | - | c | - | - | - | - | - | - |
| Ech_0660_7 | - | c | - | - | - | - | - | - |
a Seven dogs were inoculated i.v. with 2x108 E. chaffeensis mutant Ech_0660 organisms.
b Dogs were tested at the indicated time points for E. chaffeensis organisms in the blood by PCR (p) and culture recovery methods (c) as described [21].